Mrs T.S.Saraswathy Subramaniam
SpeakerAbout Mrs T.S.Saraswathy Subramaniam
Laboratory Biorisk – Monitoring and Evaluation
Mrs T.S.Saraswathy Subramaniam
Malaysia
Laboratory AUDIT
Course Synopsis
Auditing, the systematic evaluation of an organization, is inevitable at recent days. The purpose of an audit is to document whether an organization complies with all necessary requirements specified in the audit standard and applicable legislations. The purpose of safety in workplaces is to eliminate risks, implement adequate control measures to eliminate or reduce occupations safety risks to employees, visitors and other stakeholders. Safety audits will help the organization to get an independent view on various safety initiatives implemented and also provide a record of their due diligence on safety implementation. There are different approaches to a safety audit. This course shares with the participants some of the elements in laboratory audits.
Bioethics, biosafety and biosecurity issues in stem cell research
Mrs T.S.Saraswathy Subramaniam
Malaysia
Stem cells are a class of undifferentiated cells that are able to differentiate into specialized cell types. There are two types of stem cells which have the potential to be used in stem cell-based therapies: multipotent adult stem cells and pluripotent stem cells that include embryonic stem cells and induced pluripotent stem cells.
Research using human stem cell preparations holds promise for an increased understanding of the the early stages of genetic diseases, including cancer, and in future applications in cell transplantation therapies for human diseases. There is now an explosion of R & D research, worldwide using stem cells. This rapidly advancing field has shown many gaps in our knowledge and understanding of stem cell technologies and applications. Many countries have established policies and guidelines that govern research involving stem cells to ensure that such research is conducted in an ethically responsible manner. Although these policies govern bioethical issues, they are inadequate to address laboratory biosafety. Current approaches to biohazarad risk assessments and mitigation are more relevant for microbiological hazards and less appropriate for cell derived materials. Hazard characterisation for stem cells will vary depending on stem cell source, origin, type of cell and activities. Hazard identification and characterization will need to consider tumorigenesis of cells as well as risk of adventitious agents for example, blood borne pathogen risk, Mycoplasma and latent viruses which need biorisk management.
Stem cell banking through long-term storage of different stem cell platforms represents a fundamental source to preserve original features of stem cells for patient-specific clinical applications. Many institutions having biobanks storing stem cells from patients need biosecurity awareness to secure these valuable biological materials.
This presentation will address bioethics, biosafety and biosecurity issues in stem cell research.
Mrs T.S.Saraswathy Subramaniam
Malaysia
Laboratory AUDIT
Course Synopsis
Auditing, the systematic evaluation of an organization, is inevitable at recent days. The purpose of an audit is to document whether an organization complies with all necessary requirements specified in the audit standard and applicable legislations. The purpose of safety in workplaces is to eliminate risks, implement adequate control measures to eliminate or reduce occupations safety risks to employees, visitors and other stakeholders. Safety audits will help the organization to get an independent view on various safety initiatives implemented and also provide a record of their due diligence on safety implementation. There are different approaches to a safety audit. This course shares with the participants some of the elements in laboratory audits.
Bioethics, biosafety and biosecurity issues in stem cell research
Mrs T.S.Saraswathy Subramaniam
Malaysia
Stem cells are a class of undifferentiated cells that are able to differentiate into specialized cell types. There are two types of stem cells which have the potential to be used in stem cell-based therapies: multipotent adult stem cells and pluripotent stem cells that include embryonic stem cells and induced pluripotent stem cells.
Research using human stem cell preparations holds promise for an increased understanding of the the early stages of genetic diseases, including cancer, and in future applications in cell transplantation therapies for human diseases. There is now an explosion of R & D research, worldwide using stem cells. This rapidly advancing field has shown many gaps in our knowledge and understanding of stem cell technologies and applications. Many countries have established policies and guidelines that govern research involving stem cells to ensure that such research is conducted in an ethically responsible manner. Although these policies govern bioethical issues, they are inadequate to address laboratory biosafety. Current approaches to biohazarad risk assessments and mitigation are more relevant for microbiological hazards and less appropriate for cell derived materials. Hazard characterisation for stem cells will vary depending on stem cell source, origin, type of cell and activities. Hazard identification and characterization will need to consider tumorigenesis of cells as well as risk of adventitious agents for example, blood borne pathogen risk, Mycoplasma and latent viruses which need biorisk management.
Stem cell banking through long-term storage of different stem cell platforms represents a fundamental source to preserve original features of stem cells for patient-specific clinical applications. Many institutions having biobanks storing stem cells from patients need biosecurity awareness to secure these valuable biological materials.
This presentation will address bioethics, biosafety and biosecurity issues in stem cell research.
